- Input: a starting sequence and the positions to vary (or a target mutation rate).
- Output: a library of randomized sequence variants drawn from the chosen substitution scheme.
Mutagenesis
Mutagenesis
Random sequence mutagenesis at nucleotide and protein levels
Generate random sequence variants for directed-evolution libraries and robustness testing.
These tools fill chosen positions with random residues drawn from configurable schemes,
using standard nucleotide substitution rules for DNA and codon-based sampling for proteins.
They provide a model-free baseline for exploring sequence space.
Proto